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With billions in revenues at stake due to the unprecedented level of patent expiries in the mature markets - patents worth an estimated $150 billion will expire by 2018 - pharma companies are trying different strategies and expanding their portfolios beyond prescription drugs

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The global economic downturn is leading to increasing cost pressures on pharmaceutical and medical device manufacturers, notably in the mature markets of the U.S., Europe and Japan

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GDP in the BRIC countries (Brazil, Russia, India, China) is expected to rise by 190% by 2030, compared to only 50 per cent in Europe, leading to rising incomes in the emerging world and rising export opportunitiesfor life sciences manufacturers

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China is expected to jump from the world's fifth largest pharmaceutical market to the world's second largest by 2015

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As innovation in the pharmaceutical industry shifts towards specialities and biotech products, so does the need for temperature controlled and cold chain transport and storage

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The handlling of cold chain products has become much more tightly regulated across the entire pharma supply chain, with industry quality managers and governmental regulators paying closer attention to acontrolled room temperature (CRT) products

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Stricter regulatory requirements, notably around temperature control and authentication, are driving up costs and forcing manufacturers to seek more effective and efficient supply chain set-ups

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New European legislation will significantly increase data provision requirements and the burden on regulatory operations and systems, including a requirement, starting in July 2013, for all imports of active pharmaceutical ingredients (APIs) to be manufactured to GMP standards (Good Manufacturing practices), in line with European quality norms

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Regenerative medicine, which includes the replacement or repairing of human cells, tissues or organs, is regarded as a future growth field, especially thanks to 3D printing capabilities

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In 2010, 8 million people died from cancer, over a third more deaths than in 1990; and the incidence of cancer is expected to grow by another 75% by 2030, with cases nearly doubling in some.

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